A recent scan showed that the 74-year-old Rhoda star's condition had improved since she was given just three months to live.
The disease, in which cancer cells spread into the membrane surrounding the brain, is "pretty close to remission", Dr Jeremy Rudnick told NBC's Today show
That development "defies the odds", Dr Rudnick said, but he warned that her condition could change at any time.
"They develop resistance to the therapy," Dr Rudnick said of patients undergoing treatments similar to Harper's.
"And it's not a matter of if, it's a matter of when."
Harper revealed her leptomeningeal carcinomatosis diagnosis in March.
Her television character Rhoda was one of the small screen's most beloved characters of the 1970s.
She won three consecutive Emmy awards as supporting actress on The Mary Tyler Moore Show, and another for outstanding lead actress for Rhoda, which ran from 1974 to 1978.
Harper got her start in showbusiness as a dancer in several Broadway musicals, and worked with the Second City improv group.
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